Participating Companies


4D Molecular Therapeutics
Fo­cused on the dis­cov­ery and de­vel­op­ment of pro­pri­e­tary tar­get­ed AAV gene ther­a­py vec­tors and ther­a­peu­tic prod­ucts through a ro­bust dis­cov­ery plat­form, termed Ther­a­peu­tic Vec­tor Evo­lu­tion. [more in­for­ma­tion]
Aurinia Pharmaceuticals, Inc. [AUPH] US$567 MM MCap
De­vel­op­ing vo­clos­porin ad­dress­ing lu­pus nephri­tis (LN), fo­cal seg­men­tal glomeru­los­cle­ro­sis (FS­GS) & dry eye syn­drome (DES). - Dry eye top-line da­ta: ear­ly Q1 19 - LN top line da­ta: late Q4 19 - FS­GS da­ta: open la­bel da­ta: 2H 19 [more in­for­ma­tion]
CytomX Therapeutics, Inc. [CTMX] US$479 MM MCap
Lead pro­gram CX-072 is a whol­ly owned PD-L1 Pro­body cur­rent­ly be­ing studied in a Phase 1/2 study as monother­a­py and in com­bi­na­tion with ip­il­i­mumab and with ve­mu­rafenib. BMS-part­nered Pro­body of ip­il­i­mumab be­ing studied in on­go­ing Phase 1/2 trial in monother­a­py and in com­bi­na­tion with nivolumab. [more in­for­ma­tion]
Pliant Therapeutics, Inc.
Lead pro­gram is a small molecule du­al se­lec­tive in­hibi­tor of avb6/avb1 in­te­grins for IPF, pri­mary scle­ros­ing cholan­gi­tis (PSC), and re­nal fi­bro­sis - re­ceived or­phan drug desig­na­tion and will en­ter Ph1 in De­cem­ber 2018. Se­cond pro­gram is a se­lec­tive avb1 in­hibi­tor for the treat­ment of end stage liv­er fi­bro­sis and has en­tered in­to de­vel­op­ment can­di­date se­lec­tion. [more in­for­ma­tion]
Targovax [TRVX:OS] NKr404 MM MCap
En­gi­neered on­co­lyt­ic virus armed w im­mune-sti­m­u­lat­ing trans­genes for pts w solid tu­mors. Ph 1 and Ph 1/2 trials on­go­ing with mul­ti­ple da­ta read­outs in 2019-2020. CMO de­vel­oped Yer­voy at BMS. [more in­for­ma­tion]
Vericel Corporation [VCEL] US$773 MM MCap
Ad­vanced cell ther­a­py; mar­ket­ing MA­CI (car­ti­lage re­pair) and Epi­cel (skin re­place­mentt) in TAMs of $2b+. Re­cent­ly ac­quired US com­mer­cial rights for Nexo­Brid. [more in­for­ma­tion]