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ZIOPHARM Oncology Inc: The company is focused on the development of two platform technologies designed to deliver safe, effective and scalable cell- and viral-based therapies for the treatment of multiple cancer types: (1) Controlled IL-12 for turning cold tumors hot and (2) Sleeping Beauty (SB) a non-viral approach to genetically modifying cells with significantly shortened manufacturing and lower COGS. Plan to submit an IND to evaluate SB-modified TCRs targeting neoantigens to treat solid tumors in Q4 2018 followed by enrollment of patients at the NCI beginning in 2019. Currently enrolling patients in a phase 1 trials of Ad-RTS-hIL-12 as monotherapy and in combination with OPDIVO for the treatment of rGBM.
Based in...
US - New England
Clinical Stage
Phase l or ll
Disease Space
Public, USA
Market Cap
500MM - 1B
Therapeutic Modalities
Cell Therapy, Platform Technology
1 1st Ave
Charlestown, MA 02129
United States

Company Participants at Solebury Trout CEO & Investor Ski Conference 2020

  • Laurence Cooper, MD, PhD, CEO

Top 10 Holders of ZIOPHARM Oncology, Inc.

Institution OS (%) Position Mkt Val ($MM) Source Filing Date
MSD Partners LP 8.37 15,151,516 37.12 13F 6/30/20
The Vanguard Group, Inc. 8.34 15,116,645 37.04 Funds 8/31/20
Vanguard Group, Inc. (Subfiler) 8.25 14,939,888 36.60 13F 6/30/20
Miller Value Partners LLC 6.97 12,619,730 30.92 13F 6/30/20
Discovery Capital Management LLC 5.33 9,642,760 23.62 13F 6/30/20
White Rock Capital Management LP 4.34 9,297,879 22.78 Stakes 12/31/19
State Street Corp. 4.45 8,059,494 19.75 13F 6/30/20
BlackRock Fund Advisors 4.14 7,493,510 18.36 13F 6/30/20
BlackRock Institutional Trust Co. NA 3.40 6,145,989 15.06 13F 6/30/20
Geode Capital Management LLC 1.61 2,916,858 7.15 13F 6/30/20
Ownership data is sourced through FactSet.

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