ZIOPHARM Oncology Inc

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ZIOPHARM Oncology Inc: The company is focused on the development of two platform technologies designed to deliver safe, effective and scalable cell- and viral-based therapies for the treatment of multiple cancer types: (1) Controlled IL-12 for turning cold tumors hot and (2) Sleeping Beauty (SB) a non-viral approach to genetically modifying cells with significantly shortened manufacturing and lower COGS. Plan to submit an IND to evaluate SB-modified TCRs targeting neoantigens to treat solid tumors in Q4 2018 followed by enrollment of patients at the NCI beginning in 2019. Currently enrolling patients in a phase 1 trials of Ad-RTS-hIL-12 as monotherapy and in combination with OPDIVO for the treatment of rGBM.
Based in...
US - New England
Clinical Stage
Phase l or ll
Disease Space
Public, USA
Market Cap
500MM - 1B
Therapeutic Modalities
Cell Therapy, Platform Technology
1 1st Ave
Charlestown, MA 02129
United States

Company Participants at Solebury Trout CEO & Investor Ski Conference 2020

  • Laurence Cooper, MD, PhD, CEO

Top 10 Holders of ZIOPHARM Oncology, Inc.

Institution OS (%) Position Mkt Val ($MM) Source Filing Date
The Vanguard Group, Inc. 8.78 15,888,193 57.67 Funds 12/31/20
MSD Partners LP 8.37 15,151,516 55.00 Stakes 10/29/20
Vanguard Group, Inc. (Subfiler) 8.16 14,769,506 53.61 13F 9/30/20
Miller Value Partners LLC 6.84 12,385,586 44.96 13F 9/30/20
Discovery Capital Management LLC 6.07 10,994,728 39.91 Stakes 12/28/20
White Rock Capital Management LP 5.32 9,627,879 34.95 Stakes 11/5/20
State Street Corp. 5.21 9,436,633 34.25 13F 9/30/20
BlackRock Fund Advisors 4.04 7,316,194 26.56 13F 9/30/20
BlackRock Institutional Trust Co. NA 3.34 6,040,163 21.93 13F 9/30/20
Geode Capital Management LLC 1.63 2,959,235 10.74 13F 9/30/20
Ownership data is sourced through FactSet.

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