Zentalis : Discovering and developing small molecule therapeutics targeting fundamental biological pathways of cancers. Broad pipeline of potentially best-in-class oncology candidates, including ZN-c5, an oral selective estrogen receptor degrader for ER+/HER2- breast cancer, ZN-c3, a WEE1 inhibitor, ZN-d5, a BCL-2 inhibitor and ZN-e4, an EGFR inhibitor.
Based in...
US - Middle Atlantic
Clinical Stage
Phase l or ll
Disease Space
Public, USA
Market Cap
1B +
530 Seventh Avenue, Ste 2201
Corner of 39 St
New York, NY 10018
United States

Company Participants at Solebury Trout Zoomside Chat

  • Anthony Sun, CEO
  • Melissa Epperly, CFO

Lead Programs

ZN-c5: Oral SERD

oral selective estrogen receptor degrader (SERD)

Indication Phase
Breast Cancer 1/2

ZN-c3: WEE1

oral inhibitor of WEE1

Indication Phase
Solid Tumors 1/2

ZN-d5: BCL-2

oral selective inhibitor of B-cell lymphoma 2 (BCL-2)

Indication Phase
Hematologic Malignancies IND


oral, small molecule inhibitor of mutant epidermal growth factor receptor (EGFR)

Indication Phase

Top 10 Holders of Zentalis Pharmaceuticals, Inc.

Institution OS (%) Position Mkt Val ($MM) Source Filing Date
Viking Global Investors LP 10.99 3,943,284 193.73 Stakes 12/1/20
Matrix Capital Management Co. LP 10.65 3,821,739 187.76 13F 9/30/20
Fidelity Management & Research Co. LLC 7.95 2,850,720 140.06 13F 9/30/20
Tybourne Capital Management (HK) Ltd. 7.43 2,664,409 130.90 13F 9/30/20
Redmile Group LLC 6.78 2,432,408 119.50 13F 9/30/20
Citadel Advisors LLC 5.24 2,129,964 104.65 Stakes 4/3/20
Citadel LP 4.71 1,689,634 83.01 13F 9/30/20
PRIMECAP Management Co. 3.85 1,382,750 67.93 13F 9/30/20
The Vanguard Group, Inc. 3.50 1,256,957 61.75 Funds 12/31/20
Vanguard Group, Inc. (Subfiler) 3.09 1,109,753 54.52 13F 9/30/20
Ownership data is sourced through FactSet.

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