Kadmon Holdings, Inc.

Kadmon Holdings, Inc.: May 30 PDUFA data for belumosudil (cGVHD) following positive primary analysis results (May 2020); observed ORRs of 73% and 74% in 200mg QD and 200mg BID arms, respectively. Initiating 12-15 pt open-label Ph 2 in patients w diffuse cutaneous systemic sclerosis in Q1 2021. First 3-pt dose cohort successfully completed in ongoing dose-escalation Ph 1 (anti-PD-L1/IL-15 fusion protein) in patients w metastatic or locally advanced solid tumors; enrollment ongoing in next dose level. Continuing IND-enabling activities of KD045, Kadmon's next-gen ROCK inhibitor for treatment of fibrotic diseases.
Based in...
US - Middle Atlantic
Clinical Stage
Phase III
Disease Space
Autoimmune, Fibrosis, Immunotherapy, Oncology
Biotechnology, Pharmaceuticals
Public, USA
Market Cap
500MM - 1B
450 East 29th Street
New York, NY 10016
United States

Company Participants at Solebury Trout Virtual Management Access Event - 1x1 conference calls

  • Harlan W. Waksal, MD, President/CEO

Lead Programs


Indication Phase
Chronic Graft-Versus-Host Disease 2
Systemic Sclerosis 2
Idiopathic Pulmonary Fibrosis 2


Indication Phase
Wilson’s Disease 3

Top 10 Holders of Kadmon Holdings Inc Warrant 2017-28.09.22 On Kadmon Hldngs

Institution OS (%) Position Mkt Val ($MM) Source Filing Date
The Vanguard Group, Inc. 0.00 0 0.00 Funds 10/31/20
Sofinnova Ventures, Inc. 0.00 0 0.00 13F 12/31/20

Top 10 Holders of Kadmon Holdings, Inc.

Institution OS (%) Position Mkt Val ($MM) Source Filing Date
Perceptive Advisors LLC 9.84 15,711,334 73.53 Stakes 12/31/20
State Street Corp. 6.15 9,815,097 45.93 13F 12/31/20
SSgA Funds Management, Inc. 6.15 9,815,097 45.93 Stakes 12/31/20
Avidity Partners Management LP 6.00 9,570,000 44.79 Stakes 12/31/20
Point72 Asset Management LP 5.67 9,049,800 42.35 Stakes 1/13/21
The Vanguard Group, Inc. 5.64 9,002,368 42.13 Stakes 12/31/20
Vanguard Group, Inc. (Subfiler) 5.31 8,468,233 39.63 13F 12/31/20
Point72 Asset Management LP (Old) 4.92 7,857,700 36.77 13F 12/31/20
BlackRock Fund Advisors 4.92 7,856,546 36.77 13F 12/31/20
Third Point LLC 4.76 7,601,115 35.57 13F 12/31/20
Ownership data is sourced through FactSet.

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