NorthSea Therapeutics

NorthSea Therapeutics: Dutch biotech company focused on developing structurally engineered fatty acids (‘SEFAs’) for the treatment of NASH and other metabolic disorders. NST licensed the rights to its lead compound icosabutate and a library of SEFAs from Pronova BioPharma Norge AS, who developed LovazaÒ (US brand, branded OmacorÒ in Europe), a blockbuster cardiovascular drug. Icosabutate has been found safe and effective in two prior phase 2 clinical studies for treatment of hypertriglyceridemia and mixed dyslipidemia and is currently in clinical development for NASH. The icosabutate phase 2b ICONA NASH trial is scheduled to readout in the first quarter of 2023. Two additional SEFAs are in clinical development; SEFA 1024 is in phase 1 to be developed for dyslipidemia and SEFA 6179, to be developed for the orphan indication IFALD, will enter phase 1 in Q421.
Based in...
Clinical Stage
Phase l or ll
Disease Space
Fibrosis, Metabolic Disorders
Investment Participation
CrossOvers, IPO
Market Cap
Therapeutic Modalities
Small Molecule
Gooimeer 2 35
Naarden, Noord-Holland 1411 DC
The Netherlands

Company Participants at Solebury Trout Virtual Management Access Event 2021

Mats Blom
NorthSea Therapeutics, Chief Financial Officer
Mats Blom has extensive managerial experience and has held CFO positions in several public and non-public companies. He has served as CFO of Zealand Pharma A/B, a biotechnology company dual listed at Nasdaq in New York and Copenhagen, and Swedish Orphan International, an orphan drug company acquired by BioVitrum in 2009. In addition, Mats has been CFO at Modus Therapeutics, Active Biotech AB and Anoto Group AB. He has also served as a management consultant at Gemini Consulting and Ernst & Young. Mats holds a BA in Business Administration and Economics from the University of Lund and an MBA from IESE University of Navarra, Barcelona. Mats is currently board member of Hansa Biopharma, Auris Medical and Rare Thyroid Therapeutics (RTT).
Rob de Ree
NorthSea Therapeutics, Chief Executive Officer & Board Member
Prior to joining NorthSea Therapeutics B.V., Rob de Ree served as the CEO of the start-up companies Dezima Pharma, which was acquired by Amgen in 2015 and as the CEO of BMEYE which was acquired by Edwards lifesciences in 2012. Before that Rob de Ree served as the head of the licensing business of Crucell and in various national and international sales and marketing roles at Medtronic. Rob de Ree started his career in pharma in 1991 in sales and marketing at the cardiovascular division of Byk Gulden in the Netherlands. In addition Rob de Ree is currently a board member at Ventinova (chair) and Mellon medical and operating partner at Biogeneration Ventures. Rob de Ree holds an MSc in pharmacy from the University of Groningen.