Keros Therapeutics

Keros Therapeutics: clinical-stage biopharmaceutical company focused on the discovery, development and commercialization of novel treatments for patients suffering from hematologic and musculoskeletal disorders with high unmet medical need. We are a leader in understanding the role of the Transforming Growth Factor-Beta family of proteins that is a master regulator of red blood cell and platelet production as well as the growth, repair and maintenance of muscle and bone. Our lead protein therapeutic product candidate, KER-050, is being developed for the treatment of cytopenias, including anemia and thrombocytopenia, in patients with myelodysplastic syndrome and myelofibrosis. Our lead small molecule product candidate, KER-047, is being developed for the treatment of anemia resulting from elevated levels of hepcidin, the key regulator of iron absorption and recycling, as well as for the treatment of fibrodysplasia ossificans progressiva.
Based in...
US - New England
Clinical Stage
Phase l or ll
Disease Space
Metabolic Disorders, Oncology, Rare Disease
Public, USA
Market Cap
500MM - 1B
99 Hayden Avenue
Suite 120 (Building E)
Lexington, MA 02421
United States

Company Participants at Solebury Trout Virtual Management Access Event 2021

Jasbir Seehra
Keros Therapeutics, CEO
Dr. Jasbir Seehra is the Founder and serves as Chief Executive Officer, President & Board Member at Keros Therapeutics. He also serves as the Chief Scientific Officer at Ember Therapeutics. He joined Ember as chief scientific officer in 2012; and has served on Ember's scientific advisory board since the company was founded. Dr. Seehra is formerly the chief scientific officer of Acceleron Pharma, Inc., which he co-founded in 2003. Dr. Seehra has more than 25 years of experience in drug discovery, including having served as vice president of biological chemistry at Wyeth and a drug discovery consultant to AVEO Pharmaceuticals, Inc. Prior to that, he led the small molecule lead discovery effort at Genetics Institute, Inc. where he started as a bench scientist and held numerous positions with increasing responsibility. At Genetics Institute, Dr. Seehra successfully built the institute's small molecule drug discovery capabilities, including medicinal chemistry, high throughput screening and structural biology. Dr. Seehra has authored numerous publications and is an inventor on 33 patents. Dr. Seehra received his B.S. and Ph.D. in biochemistry from the University of Southampton in England. He completed his postdoctoral work at the Massachusetts Institute of Technology.
Keith Regnante
Keros Therapeutics, CFO
Keith Regnante has served as our Chief Financial Officer since February 2020. Prior to joining us, from August 2016 to January 2020, Mr. Regnante served as Chief Financial Officer at Wave Life Sciences Ltd. From February 2014 to August 2016, Mr. Regnante served as Vice President of Finance at Shire Pharmaceuticals, or Shire, a global biopharmaceutical company. Mr. Regnante also served on the Financial Leadership Team and the R&D Leadership Team while he was at Shire. From September 2013 to February 2014, he served as Head of R&D Finance for ARIAD Pharmaceuticals, Inc. From January 1999 to August 2013, Mr. Regnante held multiple finance positions at Biogen Inc., including Senior Director of Corporate Finance from 2011 to 2013, Senior Director of Worldwide R&D Finance from 2008 to 2011 and several other positions dating back to 1999. Prior to joining finance organizations for biotechnology companies, Mr. Regnante worked as a consultant at The Boston Consulting Group. He holds a B.A. in Economics from Tufts University and an M.B.A. from the MIT Sloan School of Management.

Top 10 Holders of Keros Therapeutics, Inc.

Institution OS (%) Position Mkt Val ($MM) Source Filing Date
Fidelity Management & Research Co. LLC 15.00 3,494,539 110.04 13F 6/30/21
OrbiMed Advisors LLC 7.21 1,679,417 52.88 13F 6/30/21
Consonance Capital Management LP 3.81 887,885 27.96 13F 6/30/21
State Street Corp. 2.91 678,978 21.38 13F 6/30/21
The Vanguard Group, Inc. 2.88 670,742 21.12 Funds 7/31/21
BlackRock Fund Advisors 2.79 649,539 20.45 13F 6/30/21
Vanguard Group, Inc. (Subfiler) 2.70 629,628 19.83 13F 6/30/21
Alkeon Capital Management LLC (13F Subfiler) 2.58 602,193 18.96 13F 6/30/21
Nantahala Capital Management LLC 2.57 598,880 18.86 13F 6/30/21
Eventide Asset Management LLC 1.83 427,414 13.46 13F 6/30/21
Ownership data is sourced through FactSet.

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