Affimed N.V.

Affimed N.V.: Proprietary ROCK® platform enabling generation of multi-specific antibodies is basis for its collaboration with Genentech ($96M upfront / $5B potential) to develop NK-cell engager-based therapeutics. Pipeline includes NK cell engager AFM13 (CD30/CD16A) to enter Ph 2 registration study in CD30-positive PTCL and an investigator-sponsored study by MDACC of AFM13 combined with allogeneic NK cells in relapsed/refractory CD30-positive lymphoma. IND cleared for AFM24, the company’s innate cell engager that targets EGFR-expressing solid tumors.
Based in...
Europe, USA
Clinical Stage
Phase l or ll
Disease Space
Hematology, Immuno-Oncology, Oncology
Public, USA
Market Cap
1B +
Therapeutic Modalities
Antibodies, Platform Technology
Im Neuenheimer Feld 582
Heidelberg, Baden-Wurttemberg 69120

Company Participants at Solebury Trout Corporate Access 1x1 Calls - Week of April 13

  • Adi Hoess, Ph.D., Chief Executive Officer
  • Gregory Gin, Head of Investor Relations

Lead Programs


Disease Target CD30 Immune Cell Target CD16A

Indication Phase
Hodgkin lymphoma + PD-1 1
Hodgkin lymphoma 2
Hodgkin lymphoma + adoptive NK cells Pre-clinical
CD30-positive lymphoma 2


Disease Target EGFRwt Immune Cell Target CD16A

Indication Phase
Solid tumors Pre-clinical

Top 10 Holders of Affimed N.V.

Institution OS (%) Position Mkt Val ($MM) Source Filing Date
NEA Management Co. 8.03 6,126,488 63.29 13F 12/31/20
Point72 Asset Management LP 7.39 5,635,500 58.21 Stakes 1/27/21
683 Capital Management LLC 5.63 4,289,712 44.31 13F 12/31/20
BlackRock Fund Advisors 4.88 3,723,746 38.47 13F 12/31/20
Citadel LP 4.54 3,459,116 35.73 13F 12/31/20
Point72 Asset Management LP (Old) 4.03 3,075,000 31.76 13F 12/31/20
FundLogic SASU 3.50 2,668,255 27.56 13F 12/31/20
Millennium Management LLC 2.96 2,255,617 23.30 Stakes 12/31/20
Morgan Stanley Capital Services LLC 2.50 1,905,304 19.68 13F 12/31/20
Acadian Asset Management LLC 2.43 1,852,602 19.14 13F 12/31/20
Ownership data is sourced through FactSet.

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