Idera Pharmaceuticals, Inc.: Lead candidate Tilsotolimod (TLR 9 agonist) used in comb w Ipi in PD1 refractory melanoma pts. Enrolling addl pts in Ph 2 expansion and Phase 3 enrollment expected to complete Q4 2019. Combo of ipi and Tilsotolimod appears to activate immune response in pts who have exhausted all options, e.g. PD1/CPIs. Fast Track des for Tilsotolimod (Nov’17).
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