Bellus Health: BELLUS Health- developing novel therapeutics for the treatment of chronic cough and other hypersensitization-related disorders. BELLUS' lead product candidate, BLU-5937, is being developed for the treatment of chronic cough (Phase II announced July 2020) and chronic pruritus (Phase II planned to begin 1H20).

BELLUS' Phase II for chronic cough, the RELIEF study is a dose-escalation, placebo-controlled, and crossover design to assess the efficacy, safety, and tolerability of BLU-5937, a highly selective P2X3 antagonist, at four doses; 25, 50, 100 and 200 mg, administered orally, twice-daily (BID). Approximately 65 patients with refractory chronic cough are expected to be enrolled at twelve clinical sites in the United Kingdom and United States.
Sector/Industry:
Healthcare/Biotechnology
Characteristics:
Based in...
North America
Clinical Stage
Phase l or ll
Disease Space
Respiratory
Industry
Biotechnology
Listing
Public, USA
Market Cap
100MM - 500MM
Therapeutic Modalities
Small Molecule
Website:
Profiles:
Address:
275 Armand-Frappier Boulevard
Laval, Quebec H7V 4A7
Canada

Top 10 Holders of BELLUS Health Inc.

Institution OS (%) Position Mkt Val ($MM) Source Filing Date
RTW Investments LP 10.78 5,970,230 12.96 13F 6/30/20
OrbiMed Advisors LLC 9.28 5,137,216 11.15 Stakes 6/30/20
Fidelity Management & Research Co. LLC 7.44 4,118,899 8.94 13F 6/30/20
Consonance Capital Management LP 3.47 1,922,503 4.17 13F 6/30/20
Boxer Capital LLC 3.21 1,775,000 3.85 13F 6/30/20
Cowen & Co. LLC 2.94 1,625,883 3.53 13F 6/30/20
AWM Investment Co., Inc. 2.89 1,600,000 3.47 13F 6/30/20
Eventide Asset Management LLC 2.79 1,543,000 3.35 13F 6/30/20
Marshall Wace North America LP 2.69 1,490,491 3.23 13F 6/30/20
Perceptive Advisors LLC 2.03 1,125,000 2.44 13F 6/30/20
Ownership data is sourced through FactSet.

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