Lineage Cell Therapeutics : Developing novel cell therapies for unmet medical needs. Lineage’s programs are based on its robust proprietary cell-based therapy platform and associated in-house development and manufacturing capabilities. With this platform Lineage develops and manufactures specialized, terminally differentiated human cells from its pluripotent and progenitor cell starting materials. These differentiated cells are developed to either replace or support cells that are dysfunctional or absent due to degenerative disease or traumatic injury or administered as a means of helping the body mount an effective immune response to cancer. Lineage’s clinical programs are in markets with billion dollar opportunities and include three allogeneic (“off-the-shelf”) product candidates: (i) OpRegen®, a retinal pigment epithelium transplant therapy in Phase 1/2a development for the treatment of dry age-related macular degeneration, a leading cause of blindness in the developed world; (ii) OPC1, an oligodendrocyte progenitor cell therapy in Phase 1/2a development for the treatment of acute spinal cord injuries; and (iii) VAC, an allogeneic dendritic cell therapy platform for immuno-oncology and infectious disease, currently in clinical development for the treatment of non-small cell lung cancer and in preclinical development for additional cancers and as a vaccine against infectious diseases, including SARS-CoV-2, the virus which causes COVID-19.
Sector/Industry:
Healthcare/Biotechnology
Characteristics:
Based in...
US - Pacific
Disease Space
Ophthalmology
Listing
Public, USA
Market Cap
100MM - 500MM
Website:
Profiles:
Address:
2173 Salk Avenue
Suite 200
Carlsbad, CA 92008
United States

Top 10 Holders of Lineage Cell Therapeutics, Inc.

Institution OS (%) Position Mkt Val ($MM) Source Filing Date
Broadwood Capital, Inc. 22.72 34,005,379 33.33 Stakes 7/28/20
Greenway Partners LP 4.57 6,844,642 6.71 Stakes 7/28/20
The Vanguard Group, Inc. 3.54 5,298,204 5.19 Funds 8/31/20
Vanguard Group, Inc. (Subfiler) 3.46 5,179,764 5.08 13F 6/30/20
Defender Capital LLC 3.10 4,646,290 4.55 13F 6/30/20
Prescott General Partners LLC 1.24 1,851,851 1.81 13F 6/30/20
BlackRock Institutional Trust Co. NA 1.03 1,535,837 1.51 13F 6/30/20
Geode Capital Management LLC 0.68 1,021,544 1.00 13F 6/30/20
Jane Street Group LLC 0.67 996,255 0.98 13F 6/30/20
Russell Investments Group Ltd. 0.51 761,830 0.75 13F 6/30/20
Ownership data is sourced through FactSet.

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