Developing proprietary plant-derived biomolecules to prevent metabolic diseases. Initial pipeline includes 5+ products targeting prediabetes/T2D, NAFL/NASH, hypercholesterolemia, and obesity. Lead program VALEDIA®, targeting the unaddressed prediabetes market, is currently in a Ph 2a trial for the reduction of risk factors for developing Type 2 diabetes with results expected mid 2019. In a Ph1/2 trial in healthy volunteers, VALEDIA® demonstrated a good tolerance, and during a meal test an improvement of glucose tolerance (-13% Glucose Cmax), reduction in insulin secretion (-37% Insulin AUCnet), and consequently an improvement of insulin sensitivity (41%).
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