Developing first Glx targeted antidepressant to address suicidality in bipolar depression. Lead candidate, NRX-101 in Ph 2b/3 devt (Breakthru Designation, SPA and Fast Track Designation by FDA) for Severe Bipolar Depression in pts w Acute Suicidal Ideation and Behavior. MOA: tgts NMDA and 5-HT2a receptors, shown on brain biomarker studies to achieve same beneficial neurochemical changes as SOC, ECT, w/o ECT side effects. Plans to present Ph 2 POC data later this year.
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Wilmington, DE 19801
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