Acceleron Pharma Inc: Developing TGF-beta superfamily therapeutics to treat serious and rare diseases. XLRN recently received US FDA approval with partner BMS for REBLOZYL (luspatercept-aamt) for its beta-thalassemia indication and has a PDUFA target action date of April 4th, 2020 for its MDS indication. The companies have multiple Ph2 and Ph3 trials ongoing for chronic anemia in additional patient populations of MDS and beta-thalassemia, as well as myelofibrosis. In addition to hematology, XLRN is advancing its pulmonary franchise with two Ph 2 studies in pulmonary arterial hypertension, as well as a neuromuscular program in Charcot-Marie-Tooth disease. The company expects to report topline results from Ph2 clinical trials in PAH (sotatercept) and CMT (ACE-083) in Q1 2020.
Based in...
US - New England
Clinical Stage
Phase III, Phase l or ll
Disease Space
Biotechnology, Pharmaceuticals
Public, USA
Market Cap
1B +
128 Sidney Street
Cambridge, MA 02139
United States

Top 10 Holders of Acceleron Pharma Inc

Institution OS (%) Position Mkt Val ($MM) Source Filing Date
Fidelity Management & Research Co. LLC 13.33 7,044,563 822.88 13F 6/30/20
T. Rowe Price Associates, Inc. (Investment Management) 8.90 4,702,119 549.25 13F 6/30/20
The Vanguard Group, Inc. 8.66 4,586,323 535.73 Funds 9/30/20
Vanguard Group, Inc. (Subfiler) 8.06 4,261,023 497.73 13F 6/30/20
Farallon Capital Management LLC 3.97 2,100,000 245.30 13F 6/30/20
Wellington Management Co. LLP 2.90 1,533,911 179.18 13F 6/30/20
Artal Group SA 2.65 1,400,000 163.53 13F 6/30/20
BlackRock Institutional Trust Co. NA 2.49 1,316,106 153.73 13F 6/30/20
Alkeon Capital Management LLC (13F Subfiler) 2.30 1,214,345 141.85 13F 6/30/20
BlackRock Fund Advisors 2.27 1,199,438 140.11 13F 6/30/20
Ownership data is sourced through FactSet.

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