Acceleron Pharma Inc: Developing TGF-beta superfamily therapeutics to treat serious and rare diseases. XLRN recently received US FDA approval with partner BMS for REBLOZYL (luspatercept-aamt) for its beta-thalassemia indication and has a PDUFA target action date of April 4th, 2020 for its MDS indication. The companies have multiple Ph2 and Ph3 trials ongoing for chronic anemia in additional patient populations of MDS and beta-thalassemia, as well as myelofibrosis. In addition to hematology, XLRN is advancing its pulmonary franchise with two Ph 2 studies in pulmonary arterial hypertension, as well as a neuromuscular program in Charcot-Marie-Tooth disease. The company expects to report topline results from Ph2 clinical trials in PAH (sotatercept) and CMT (ACE-083) in Q1 2020.
Based in...
US - New England
Clinical Stage
Phase III, Phase l or ll
Disease Space
Biotechnology, Pharmaceuticals
Public, USA
Market Cap
1B +
128 Sidney Street
Cambridge, MA 02139
United States

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Top 10 Holders of Acceleron Pharma Inc

Institution OS (%) Position Mkt Val ($MM) Source Filing Date
Fidelity Management & Research Co. LLC 13.41 7,062,694 696.31 13F 2020-03-31
The Vanguard Group, Inc. 8.09 4,260,079 420.00 Funds 2020-04-30
Vanguard Group, Inc. (Subfiler) 7.85 4,137,124 407.88 13F 2020-03-31
T. Rowe Price Associates, Inc. (Investment Management) 7.70 4,057,954 400.07 13F 2020-03-31
Farallon Capital Management LLC 4.13 2,175,000 214.43 13F 2020-03-31
BlackRock Fund Advisors 3.71 1,955,552 192.80 13F 2020-03-31
Wellington Management Co. LLP 3.66 1,929,566 190.24 13F 2020-03-31
Artal Group SA 2.85 1,500,000 147.89 13F 2020-03-31
State Street Corp. 2.80 1,476,926 145.61 13F 2020-03-31
BlackRock Institutional Trust Co. NA 2.51 1,324,263 130.56 13F 2020-03-31
Ownership data is sourced through FactSet.

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