Marker Therapeutics: A clinical-stage immuno-oncology company with the potential to significantly disrupt the current cell therapy landscape. The Company is developing a portfolio of non-genetically modified, multi-antigen T cell therapies, which are able to recognize and kill heterogeneous tumors more effectively than conventional single-antigen CAR-T/TCR approaches. Compared to current engineered CAR-T therapies, Marker's products could potentially be less expensive, easier to manufacture, be less toxic and show clinical benefit with less cell volume and faster administration time.

Marker's current MultiTAA cell therapy is looking to initiate a Phase II study in AML in 2020 with enrollment completion anticipated in 2H20. Marker announced an updated study protocol for the Ph 2 trial in February 2020. The company also has a T-cell vaccine program, currently being studied in breast cancer.
Sector/Industry:
Healthcare/Biotechnology
Characteristics:
Based in...
US - West South Central
Clinical Stage
Phase l or ll
Disease Space
Immuno-Oncology
Industry
Biotechnology, Pharmaceuticals
Listing
Public, USA
Market Cap
<100MM
Therapeutic Modalities
Cell Therapy
Website:
Address:
3200 Southwest Fwy #2240, Phoenix Tower
Houston, TX 77027
United States

Top 10 Holders of Marker Therapeutics, Inc.

Institution OS (%) Position Mkt Val ($MM) Source Filing Date
NEA Management Co. 10.95 5,000,000 7.65 13F 6/30/20
Eastern Capital Ltd. 8.87 4,050,001 6.20 Stakes 6/16/20
Aisling Capital Management LP 4.38 2,000,000 3.06 13F 6/30/20
The Vanguard Group, Inc. 3.34 1,524,905 2.33 Funds 8/31/20
Vanguard Group, Inc. (Subfiler) 3.23 1,475,759 2.26 13F 6/30/20
BlackRock Fund Advisors 2.24 1,023,660 1.57 13F 6/30/20
BlackRock Institutional Trust Co. NA 1.70 777,788 1.19 13F 6/30/20
State Street Corp. 1.16 529,671 0.81 13F 6/30/20
Geode Capital Management LLC 1.04 473,344 0.72 13F 6/30/20
Northern Trust Corp. 0.81 369,889 0.57 13F 6/30/20
Ownership data is sourced through FactSet.

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