Modular ROCK™platform enabling multi-specific NK / T-cell bi-and tri-specific Abs. Aug 2018 deal with Genentech ($96M upfront / $5B potential) to develop NK-cell engager-based therapeutics through application of ROCK platform. Lead NK cell engager AFM13 (CD30/CD16A) in Ph1b combo w/ Keytruda in Hodgkins and Ph2a (mono) in CD30(+) lymphoma including TCL. T-cell engager AFM11 (CD19/CD3) in 2 dose escalation studies in ALL and NHL.
Phase l or ll
Hematology, Immuno-Oncology, Oncology
100MM - 500MM
Antibodies, Platform Technology
Im Neuenheimer Feld 582
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